Benjamin Cravatt, PhD, professor of chemistry and the Gilula Chair of Chemical Biology at Scripps Research, has been awarded the 2022 Wolf Prize in Chemistry, one of the most prestigious awards in the field. The Wolf Foundation awarded him the prize for “developing activity-based protein profiling, which has emerged as a powerful and widely used chemical proteomic strategy to characterize enzyme function in native biological systems.” The foundation added that Cravatt went on to use this approach to characterize numerous enzymes which play critical roles in human biology and disease, including in the endocannabinoid system, which consists of lipid transmitters involved in appetite regulation, pain sensation, mood, memory and other physiological processes.