Clinical trials are a critical part of advancing new medical innovations from the laboratory to patients. Traditional clinic-based trials, however, have several limitations. Trial participation is limited to those with access to the clinic and data gathered during those visits provides an incomplete, episodic picture of a person’s response to the intervention. Scripps Research is transforming that scenario. In this Front Row lecture, Katie Baca-Motes, MBA, and Julia Moore Vogel, MBA, PhD, will share how scientists at the Scripps Research seek to re-engineer trial participation by tapping into the power of digital technologies.